Socioeconomic and psychosocial predictors of interleukin-6 in the MIDUS national sample.
نویسندگان
چکیده
OBJECTIVE To investigate whether psychosocial factors (i.e., depression, anxiety, and well-being) moderated educational gradients in interleukin-6 (IL-6) levels using data from the Survey of Midlife Development in the U.S. (MIDUS). The influences of educational attainment and psychosocial factors on IL-6 in middle aged and older adults were also examined. DESIGN Telephone interviews and mail surveys were utilized to collect educational attainment and psychosocial information from respondents (N = 1028). Respondents also participated in an overnight clinic visit, during which health information and a fasting blood sample were obtained. MAIN OUTCOME MEASURES Serum levels of IL-6. RESULTS Greater educational attainment predicted lower levels of IL-6 independent of age and gender, although this effect was attenuated after taking health behaviors, body mass index, waist-to-hip ratio, and chronic illnesses into account. Psychological well-being interacted with education to predict IL-6, such that for those with less education, higher well-being was associated with lower levels of IL-6. CONCLUSION The findings indicate a strong association between education and inflammation, which can be further moderated by psychosocial factors. The health benefits associated with psychological well-being were particularly evident for individuals with low educational attainment.
منابع مشابه
Health Psychology Socioeconomic and Psychosocial Predictors of Interleukin-6 in the MIDUS National Sample
متن کامل
Income, education, and inflammation: differential associations in a national probability sample (The MIDUS study).
OBJECTIVE To examine the associations between income and education and three markers of inflammation: interleukin-6 (IL-6), C-reactive protein (CRP), and fibrinogen. Socioeconomic status is inversely linked with health outcomes, but the biological processes by which social position "gets under the skin" to affect health are poorly understood. METHOD Cross-sectional analyses involved participa...
متن کاملVarieties of Resilience in MIDUS.
Population-based studies of health typically focus on psychosocial contributors to illness and disease. We examine findings from a national longitudinal study of American adults, known as MIDUS (Midlife in the U.S.) to examine the role of psychosocial factors in promoting resilience, defined as the maintenance, recovery, or improvement in health following challenge. Classic studies of resilienc...
متن کاملThe Value of Interleukin-8 and Interleukin-6 in Cervical Secretions as Predictors of Preterm Delivery
Background and Objective: Preterm birth occurs in 8% to 11% of all pregnancies and is responsible for 75% to 80% of all neonatal deaths. Cytokines may be involved in the etiology of preterm birth through their stimulation of prostaglandin synthesis. Cytokines may be released intocervicovaginal fluid during the breakdown of the chorio-decidual adhesion or from an inflammatory reactio...
متن کاملContribution of psychosocial factors to socioeconomic differences in health.
The National Survey of Mid-life Developments in the United States (MIDUS) is one of several studies that demonstrate socioeconomic gradients in mortality during midlife. When MIDUS findings on self-reported health, waist to hip ratio, and psychological well-being were analyzed for their possible roles in generating socioeconomic differences in health, they revealed clear educational gradients f...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Health psychology : official journal of the Division of Health Psychology, American Psychological Association
دوره 29 6 شماره
صفحات -
تاریخ انتشار 2010